THC vs CBD Marijuana Strain : What’s the Difference?

Last Updated : July 28, 2020 by canadianmarijuanaproducts

Cannabinoids are well-organized chemicals found mainly in the cannabis plant, making it a plant as necessary as a medicine. Although cannabis carries more than 70 different cannabinoids, most of the medical profits of the plant are connected to the two most prevailing cannabinoids; THC and CBD. Here, in this article, we’ll understand an overview of the difference between THC v/s CBD.

THC vs CBD Marijuana

But first, let’s learn the basics. Cannabis is a plant that offers a thick material full of compounds called cannabinoids. There are more than 100 of these substances in cannabis. They generate drug-like reactions in your body.


THC (tetrahydrocannabinol) and CBD (cannabidiol) are the most prevalent cannabinoids found in cannabis products.

Let’s start with tetrahydrocannabinol known as THC!

What is THC (tetrahydrocannabinol)


THC is the chief psychoactive component of the cannabis plant. In other words, THC is the main agent accountable for producing the ‘high’ connected with recreational cannabis usage.

This composite works, in part, by simulating the effects of anandamide and 2-AG. These neurotransmitters are created naturally by the human body and help change sleeping and eating manners, the understanding of pain, and many other physical functions.

The effects of THC include:

  • Relaxation
  • Modified sensations of vision, smell, and sound
  • Tiredness
  • Food craving
  • Controlled aggression

Benefits of THC

Research studies show that THC may help in treating:

  • Side Effects of Chemotherapy
  • Multiple Sclerosis
  • Spinal injury: Lessen tremors
  • Sickness and vomiting
  • Chronic pain
  • Inflammation
  • Digestive health

What is CBD (cannabidiol)

Cannabidiol is one of the most critical cannabinoids carried by the cannabis plant. It exists both in agricultural hemp and medical marijuana.

While cannabinoids exist within many other plants in nature, cannabis is the only plant identified to carry CBD.

CBD has the same chemical structure as THC, with the atoms in a different form. This slight variation makes THC to produce a psychoactive effect, while CBD does not.

This revelation indicates that when you take CBD for medical use, you will more likely feel the relief of your unwanted trouble, with little or no noticeable effect on your cognitive abilities.

Benefits of CBD

Many research studies related to cannabis have shown that CBD can be useful in helping with:

  • Pain (neuropathic, chronic, cancer-related, etc.)
  • Multiple Sclerosis (MS)
  • Amyotrophic Lateral Sclerosis (ALS)
  • Parkinson’s
  • Dyskinesia
  • Depression
  • Rheumatoid Arthritis
  • Nausea
  • Anxiety
  • ADHD

THC vs CBD Cannabinoids

THC and CBD both can be discovered in both marijuana and hemp. Marijuana carries much more THC than hemp, while hemp has a lot of CBD. Many people confuse marijuana with hemp. Let’s clear that confusion first!

Marijuana (High THC) and Hemp (High CBD)

Hemp and marijuana are both acquired from cannabis plants, but under the 2018 Farm Bill, industrial hemp can’t be more than 0.3% THC legal.

That suggests that hemp-derived CBD, which is unusually psychoactive, is legal all across the nation regardless of whether or not cannabis is permitted in a particular state.

That’s not to assume that all CBD products will be available publicly. The Food and Drug Administration still recognizes CBD to be a “drug ingredient” and has strict regulations for CBD in edibles or health products. To know more about the difference between Marijuana and Hemp, Click Here!

Let’s move forward with the fundamental differences between THC v/s CBD. For your convenience, we have divided the review into the following sections:

The similarity between THC and CBD

Both THC and CBD have the exact identical molecular formation: 21 carbon atoms, 30 hydrogen atoms, and 2 oxygen atoms.

A slight variation in the formation of the atoms is responsible for the differing impacts on your body.

Both of these cannabinoids are chemically similar to your body’s endocannabinoids. This allows them to interact with your cannabinoid receptors.

The interplay influences discharge of neurotransmitters in your brain. Neurotransmitters are chemicals accountable for carrying messages between cells and have parts in pain, resistant function, anxiety, and sleep, to mention a few.

THC and CBD have the same outcomes for handling medical conditions. However, there is some difference in the uses of each element.

What’s the Difference between THC and CBD?

The major difference separating THC and CBD is the outcomes they have on you. To simplify, we can say that THC gets you ‘high’ while CBD won’t.

This is because CBD does not connect entirely to our endocannabinoid system – the body’s unique system that controls factors such as sleep, hunger, and the immune system. It is this binding thing that gives you that feeling of ‘high.’

THC launches a psychological response through the endocannabinoid system’s cannabinoid 1 receptors (CBD1), located mainly in the central nervous system and the brain. When the CB1 receptor is stimulated, it generates a psychoactive impact.

Without getting much into scientific information, CBD and THC may share the identical chemical structure, but their atomic designs are different.

While THC and CBD both discovered in cannabis plants, THC is most prevalent in other forms of cannabis, while CBD can be discovered in higher amounts in hemp.

 Medical studies have recommended that CBD can help much to people with medical conditions such as anxiety and depression.

On the other hand, THC might worsen anxiety and develop paranoia in some users, as proposed by other medical studies.

However, some researches have implied that when THC is merged with CBD, the adverse impacts are reduced.

THC vs CBD : Psychoactive components


Despite their same chemical compositions, CBD and THC don’t have similar psychoactive effects.

THC connects with the cannabinoid 1 (CB1) receptors in the brain. It produces a ‘high’ or feeling of euphoria when consumed properly.

CBD unites very weakly, if at all, to CB1 receptors. It requires THC to bind to the CB1 receptor and, in change, can help to lessen some of the undesired psychoactive results of THC, such as euphoria or sedation.

CBD is also a psychoactive, just not in the same way as THC. It doesn’t provide the high compared with THC. CBD is proved to help with anxiety, depression, and seizures.

THC vs CBD: Legality


Cannabis is illegal in most of the countries in the world, and CBD is legal in many nations around the globe. However, because CBD is an essence from the cannabis plant, its legitimacy is steeped in lots of laws and legislation.

This indicates that not everybody can cultivate, produce, or buy the products. In addition to this, each nation has its own regulations that are ever-changing concerning cannabis.

Authorities are changing the laws regarding cannabis all the time. Many states have permitted medical marijuana, including THC, for many uses, but it is still prohibited under federal law. Some provinces have made recreational cannabis with THC legal for individual usage.

As a part of the Farm Bill in December 2018, Congress authorized hemp. But there are still laws about where and how you can trade products that contain CBD.

You can’t sell some across the state borders, for instance. All CBD goods are illegal if they’re sold with the assurance of medical profits.

Other kinds of cannabis and cannabis-derived CBD will offer you a great high due to their high volumes of THC, nearly around 30%. It indicates that they’re often prohibited in several nations around the world.

However, when CBD is obtained from the hemp plant, it has such minute levels of THC that numerous countries have no regulations against its usage.

Kindly check your state’s legislation before purchasing products with THC or CBD. To know more about the legality of marijuana in Canada, Click Here!

THC v/s CBD: Usage and Dose


“Start low and go slow!” This is the phrase you will hear from many experts when it comes to using cannabis.

Because it is the psychoactive composite, it can generate sensations of euphoria, a head high, and in some users, anxiety.

There are many alternatives ways available in the market to consume THC and CBD. Some of them are as follows:

  • Tinctures are herbal essences produced from infusing plants in alcohol. You can use these through a dropper applied under the tongue. (Just make sure to let the droplets soak and not swish the fluid around in your mouth.)
  • Oils require a carrier oil such as coconut oil or hemp seed oil. Just like tinctures, you can take THC or CBD oils by using a dropper under the tongue.
  • Edibles like THC and CBD gummies are much popular because of their flavor. Other edibles include weed cookies, weed brownies, weed candies, and weed lollipops.
  • Vaping is also a popular method to take THC or CBD but can end in lung irritation if it’s made of cheap carrier fluids. If you’re going to vape CBD, don’t forget to check the ingredients before purchasing any products. It shouldn’t use the same components as nicotine vapes. 
  • Patches enable users to take THC or CBD by their skin. With a single adherent patch, you can perceive the benefits of THC and CBD without requiring to vape or consume edibles.
  • Tablets are more comfortable to ingest and an excellent solution for users who prefer not to smoke. Taking pills is a different way where patients can take cannabis without losing its medicinal benefits.

Precise dosage is significant with cannabis products, as cannabinoids do not develop in therapeutic results with a higher dosage as most medications do.

While cannabis is very safe to use, the dosage is the key to obtain the most significant positive outcomes and withdrawing adverse impacts like an unusual level of psychoactivity or desensitization to cannabinoids.

With cannabis, less is more while unlocking its advantages.

If you reside in a country with legal recreational marijuana, you can utilize cannabis products in a variety of forms. It will be up to you to choose which option works best for you — and at what dosage.

So, initially, you’ll have to do some experimenting with all the options available. It’s best to start with a low dose and move up over a few days when you begin.

Because CBD is such a newcomer in the market, there aren’t set instructions on how to handle it. The dosage differs based on the person and the disease.

There are specific measurements that you need to get while dozing your THC or CBD. Click Here! If you want to know how to dose your THC or CBD.

THC v/s CBD: Medical Benefits


THC is nearly equivalent to its effectiveness compared to CBD. Some of the therapeutic conditions that benefit from THC usage include:

  • Chronic Pain
  • Side effects of chemotherapy – Lessen nausea and vomiting while boosting appetite
  • Multiple Sclerosis – Repair spasticity and bladder function while defeating painful spasms and central pain
  • Glaucoma – Decrease pressure inside the eye
  • AIDS – Relieve symptoms by arousing appetite and digestion
  • Spinal injury – Reduce tremors

Many studies based on weed have indicated that CBD can be beneficial in treating various medical conditions, including:

  • Schizophrenia – Decrease psychotic symptoms
  • Seizures — Reduce the number of illnesses and can soothe painful traits
  • Social Anxiety Disorder – Lower anxiety
  • Depression – Help in overcoming depressive signs
  • Side effects of cancer treatment – Reduce pain and nausea while stimulating hunger

Why is CBD Used More Than THC for Medical Treatments?

THC is categorized as an illegal drug with significant quick and long-term cognitive side effects, including damaged thinking and reasoning, decreased ability to think and organize, modified decision-making, and reduced power overdrives.

Also, the chronic usage of THC can be linked with notable abnormalities in the heart and brain.

CBD doesn’t generate the euphoric cognitive effects of THC. In fact, CBD neutralizes the psychoactive effects of THC, both in plant form and when applied from the extract.

Weed plants carrying small amounts of CBD and high levels of THC end in a robust stoned feeling, while plants that have more CBD and less THC produce a weaker buzz.

Given the rising demand for medical marijuana, growers are currently producing strains with higher CBD to THC proportions to reduce the psychoactive adverse effects.

Overall, the lower health perils of CBD in union with its absence of euphoria make it a perfect applicant for patients bothered about feeling high.

However, in order with low doses of THC, CBD can deliver even more significant medical advantages.

THC v/s CBD: Side Effects


CBD is well endured, even in high doses. Research Trusted Source recommends any side effects that happen with CBD use are likely the outcome of drug-to-drug intercommunications between CBD and other medicines you may be taking.

THC generates transient side effects, such as:

  • Increased heart rate
  • Coordination difficulties
  • Dry mouth
  • Red eyes
  • Slower response times
  • Memory loss
  • Anxiety

The side effects of CBD might include:

  • Appetite fluctuations
  • Fatigue
  • Weight loss
  • Dizziness
  • Diarrhea

One thing you need to remember that these side effects are part of the combinations of psychoactive attributes.

Neither compound is fatal.

However, a high amount of THC application may be related to long-term adverse psychiatric effects. This is particularly right for teenagers who use large amounts of THC, though there’s no convincing proof that utilizing cannabis produces psychiatric disorders like schizophrenia.

Final Thoughts

Following the effects of CBD is misleading when THC is also mentioned sometimes. Do both of them originate from the same plant? Do they get you high? And how do they differ precisely?

To help you find the answers to such questions, we’ve put together this informative article on an Overview of THC v/s CBD to describe the differences between THC and CBD.

CBD and THC both have therapeutic benefits. They’re also both regarded as safe, but you should analyze the probability of side effects and their interactions with other medications you’re taking. You should consult your doctor or qualified cannabis or CBD clinician before you start using it if you have any inquiries.

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